G.A.P. Pharmaceuticals S.A.
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Packaging Boxes containing 20 soft gelatin capsules, 2 blisters (PVC/Aluminium foil).

Vitamin A is a fat soluble vitamin essential for growth, tissue development and vision, whose deficiency may lead to xerophthalmia and blindness.
Normal adult liver storage is sufficient to satisfy two years requirements of vitamin A.
Vitamin A and E are absorbed from the gastrointestinal (GI) tract using a mechanism similar to that for the other fat-soluble vitamins and are dependent on the presence of bile and normal pancreatic function. Vitamin A is hydrolysed to retinol, which is then absorbed and re-esterified. Some retinol is stored in the liver. It is released from the liver bound to a specific retinol-binding protein in the blood. The retinol not stored in the liver undergoes glucuronide conjugation and subsequent oxidation to retinal and retinoic acid; these and other metabolites are excreted in the faeces.
Vitamin E is widely distributed to all tissues and stored in adipose tissue. Vitamin E appears in breast milk but is poorly transferred across the placenta. Some vitamin E is metabolised in the liver to glucuronides of tocopheronic acid and its γ -lactone. Some is excreted in the urine, but most of the dose is slowly excreted in the bile.
Vitamin's E primary role is the prevention of oxidation of polyunsaturated fatty acids. Vitamin E reacts with free radicals which are the cause of oxidative damage to cell membranes, without the formation of other free radicals in the process. Vitamin E enhances vitamin A utilisation and suppresses platelet aggregation.

Aghisilaou 46, 173 41 Aθήνα,
Tel: 210-9310980-4, Fax: 210-9338759 email : gap@gap.gr